课程编号 | 课程名称 | 课程级别 | 学时 |
106121 | 兽医药理学研究进展 | 博士课 | 48 |
106234 | 分子药理学 | 博士课 | 32 |
106214 | 毒理学研究进展 | 博士课 | 32 |
206308 | 兽医药代动力学 | 硕士课 | 48 |
206364 | 抗菌药物专题 | 硕士课 | 48 |
306316 | 兽医药理学专题与案例分析 | 硕士课 | 32 |
1. 《二氢杨梅素调控NLRP3炎症小体的靶标确证及干预内毒素致鸡细胞焦亡的机制研究》,国家自然科学基金项目,2024-2027;
2. 《实验羊驼生物学数据的测定及在新兽药研发中的初步应用研究》,“十四五”国家重点研发计划项目子课题,2022-2026;
3. 《建立SPF猪生物学特性描述规范和数据库》,“十三五”国家重点研发计划课题子课题,2017-2020;
4.《HNF-1调节GSTA1表达的机制及与JNK细胞信号通路关系研究》,国家自然科学基金项目,2015-2018。
1、Lina Jia,Yingchao Gong,Xinru Jiang,Xianan Fan,Zhenghua Ji,Tianwen Ma,Rui Li,Fangping Liu*,Ginkgolide C
inhibits ROS-mediated activation of NLRP3 inflammasome in chondrocytes to
ameliorate osteoarthritis,JOURNAL OF
ETHNOPHARMACOLOGY, 2024, 325: 117887.
2、Chenxi Shi , Jiaqi Wang , Ruichen Zhang , Muhammad Ishfaq , Ying
Li , Ruihui Zhang , Chuanbiao Si , Rui Li, Changwen Li and Fangping Liu*. Dihydromyricetin alleviates Escherichia coli
lipopolysaccharide-induced hepatic injury in chickens by inhibiting the NLRP3
infammasome,VETERINARY RESEARCH, 2022, 53(1):6,1-16.
3、Yuanyuan Zhang, Bingke Ma, Shuangshuang Hao, Jiaqi Wang, Ruichen
Zhang, Muhammad Ishfaq, Chenxi Shi, Liang Yuan, Rui Li, Changwen Li, Fangping Liu*. Drug-induced
liver injury: Oltipraz and C2-ceramide intervene HNF-1α/GSTA1 expression via JNK signaling
pathway, Journal of Applied Toxicology,2021,
41(12): 2011-2020.
4、Yicong Chang, Jingshan He, Bingke Ma, Muhammad Ishfaq, Jiaqi Wang,
Ruichen Zhang, Liang Yuan, Jiarui Liu, Changwen Li, Fangping Liu*. Prevention of acetaminophen-induced hepatocyte
injury: JNK inhibition and GSTA1 involvement, Molecular & Cellular
Toxicology, 2021,17(2): 161-168.
5、Changwen Li, Feng Wang, Rui Li, Muhammad Ishfaq, Hongyan Chen, Fangping Liu*, Yun Liu*. Hematologic and biochemical
reference intervals for 1-month-old specific-pathogen- free Landrace pigs, Veterinary Clinical Pathology,2021,
50(1): 76-80.
6、Yicong Chang , Liang Yuan , Jiarui Liu, Ishfaq Muhammad , Chuanbao
Cao, Chenxi Shi , Yuanyuan Zhang , Rui Li, Changwen Li and Fangping Liu*. Dihydromyricetin attenuates Escherichia
coli lipopolysaccharide-induced ileum injury in chickens by inhibiting NLRP3
infammasome and TLR4/NF-κB signalling pathway, VETERINARY RESEARCH, 2020,51(1):72 , 1-12.
7、Chenxi Shi, Beili Hao, Yang Yang, Ishfaq Muhammad,
Yuanyuan Zhang, Yicong Chang, Ying Li, Changwen Li, Rui Li, Fangping Liu*. JNK signaling pathway mediates acetaminophen-induced hepatotoxicity
accompanied by changes of glutathione S-transferase A1 content and
expression, FRONTIERS IN PHARMACOLOGY, 2019, Volume 10, Article 1092.
8、Yicong Chang, Feng Wang, Yang Yang, Yuanyuan
Zhang, Ishfaq Muhammad, Rui Li, Changwen Li, Ying Li, Chenxi
Shi, Xin Ma, Beili Hao, Fangping
Liu*. Acetaminophen-induced hepatocyte injury: C2-ceramide and
oltipraz intervention, HNF-1 and GSTA1 changes,Journal
of Applied Toxicology,2019, 39(12): 1640-1650.
9、Ying Li, Beili Hao, Ishfaq Muhammad,
Yuanyuan Zhang, Yang Yang, Chenxi Shi, Yicong Chang, Rui Li, Changwen
Li and Fangping Liu*. Acetaminophen-induced
reduction in glutathione-S-transferase A1 in hepatocytes: A role for hepatic
nuclear factor 1α and its response element,Biochemical
and Biophysical Research Communications, 2019,516:251-257.
10、Rui Li, Feng Wang, Yuanyuan Zhang, Changwen Li, Changyou Xia, Hongyan Chen, Xiaoye Lu,
Fangping Liu*. Comparison of
hematologic and biochemical reference values in specific-pathogen-free
1-month-old Yorkshire pigs and Yorkshire-Landrace crossbred pigs,Canadian Journal of Veterinary Research, 2019,83(4):285-290.
11、Chenxi Shi, Minmin Li, Ishfaq Muhammad, Xin Ma,
Yicong Chang, Rui Li, Changwen Li, Jingshan He and Fangping Liu*. Combination of berberine and ciprofloxacin reduces
multi-resistant Salmonella strain biofilm formation by depressing mRNA
expressions of luxS, rpoE, and ompR, JOURNAL OF VETERINARY SCIENCE, 2018.
19(6): 808-816.
12、Xin Ma , Yicong Chang, Ishfaq Muhammad, Chenxi Shi , Rui Li ,
Changwen Li, Zhi Li , Yuexia Lin , Qing Han and Fangping Liu*. Effects of C2-ceramide and Oltipraz on Hepatocyte
Nuclear Factor-1 and Glutathione S-transferase A1 in Acetaminophen-mediated
Acute Mice Liver Injury, frontiers in Pharmacology, 2018, Volume 9, Article
1009.
13、Ying Li, Zhi Li, Changwen Li, Xin Ma, Yicong Chang, Chenxi Shi,
Jingshan He, Rui Li, Ishfaq Muhammad , Fangping
Liu*. Evaluation of hepatoprotective activity of Syringa oblata leaves
ethanol extract with the indicator of glutathione S-transferase A1, Revista
Brasileira de Farmacognosia, 2018, 28(4): 489-494.
14、刘芳萍副主编。《兽医药理学》(第二版),国家林业和草原局普通高等教育“十三五“规划教材,中国林业出版社,2021.8.
15、刘芳萍副主编。《兽医药物分析》(第二版),普通高等教育农业部“十二五”规划教材,中国农业出版社,2018.4.
16、刘芳萍参译,《禽病学》(第十四版),辽宁科学技术出版社,2022.5.
获黑龙江省畜牧科技奖一等奖1项、黑龙江省教委科技进步三等奖1项、国家发明专利1项。现任农业农村部兽药评审专家,国家自然科学基金评议专家,国家科技专家库专家,中国畜牧兽医学会兽医药理学与毒理学分会常务理事,黑龙江省畜牧兽医学会理事,黑龙江省生理科学会理事等。