姓名:王丽
性别:女
出生年月:1984-09-25
职称:副教授
办公电话:
工作单位:东北农业大学动物医学学院
E-mail:wanglicau@163.com
开设研究生课程情况
课程编号 课程名称 课程级别 学时
近五年主持科研项目概况

1. “十四五”国家重点研发计划子课题,2022YFD1800805,表达PEDV保护性抗原重组乳酸菌口服疫苗的研制,2022.11-2025.1250万元,在研,主持

2. 国家自然科学基金青年基金,31702260TGEV Nsp2诱导宿主炎症防疫的机制及其与病毒致病性的关系,2018.1- 2020.1225万元,已结题,主持

3. “十二五农村领域国家科技计划,2015BAD12B02-7,猪病毒性腹泻的重组乳酸杆菌活载体疫苗研制与开发,2015.4-2019.1290万元,已结题,主持

4. 中国博士后科学基金面上项目,2016M601408,猪传染性胃肠炎病毒致炎相关蛋白与其致病性关系的研究,2016.11-2019.115万元,已结题,主持

5. 黑龙江省科技创新人才项目,UNPYSCT-2018147,猪传染性胃肠炎病毒非结构蛋白与其致病性的关系,2018.8- 2021.910万元,已结题,主持

6. 国家疫病病原生物学国家重点实验室开放基金课题,SKLVEB2018KEKT004PEDVTGEVPoRV的重组乳酸杆菌活载体三联疫苗的研制,2018.12-2020.1110万元,已结题,主持

7. 东北农业大学学术骨干项目,TGEV感染诱导宿主细胞凋亡的机制,2020.1-2022.1210万元,已结题,主持

8. 东北农业大学青年才俊项目,16QC24,调控NF-κB信号通路的猪传染性胃肠炎病毒蛋白的筛选及其作用机制,2016.6-2018.66万元,已结题,主持


近五年项目获奖概况

1. 基因工程乳素菌微生态制剂的分子设计及机制研究,黑龙江省畜牧科技奖,一等奖,第3名,2018


近五年代表性著作、论文

1. Wang Y, Sun A, Sun Y, Zhang S, Xia T, Guo T, Hao Z, Sun L, JiangY, Qiao X, Cui W, Tang L, Xu Y, Li Y, Wang L*. Porcine transmissible gastroenteritis virus inhibits NF-kB activity via nonstructural protein 3 to evade host immunesystem.Virology Journal.2019,16:97-109.

2. Wang L, Zhao D, Sun B,Yu M, Wang Y, Ru Y, Jiang Y, Qiao X, Cui W,Zhou H, LiY, XuY,Tang L. Oral vaccination with the porcine circovirus type 2 (PCV-2) capsid protein expressed by Lactococcus lactis induces a specific immune response against PCV-2 in mice. Journal of Applied Microbiology. 2019,128(1):74-87.

3. Wang L, Xia T, Guo T, Ru Y , Jiang Y, Cui W, Zhou H, Qiao X, Tang L, Xu Y, Li Y. Recombinant Lactobacillus casei Expressing Capsid Protein VP60 can Serve as Vaccine Against Rabbit Hemorrhagic Disease Virus in Rabbits.Vaccines.2019,7(4):E172.

4. Wang L, Qiao X, Zhang S, Qin Y, Guo T, Hao Z, Sun L, Wang X, Wang Y, Jiang Y, Tang L, Xu Y, Li Y. Porcine transmissible gastroenteritis virus nonstructural protein 2 contributes to inflammation via NF-κB activation,Virulence.2018,9(1):1685-1698.

5. Ma S, Wang L, Huang X, Wang X, Chen S, Shi W, Qiao X, Jiang Y, Tang L, Xu Y, Li Y. Oral recombinant Lactobacillus vaccine targeting the intestinal microfold cells and dendritic cells for delivering the core neutralizing epitope of porcine epidemic diarrhea virus. Microb CellFact. 2018,9:17(1):20.

6. WuY, Wang L, GuoT, JiangY, Qiao X, Sun L, Liu M, Tang L, XuY, LiY. Identification of amino acid residues in infectious hematopoietic necrosis virus (IHNV) NV protein necessary for viral replication and pathogenicity.Fish Shellfish Immunol.2018,79:294-302.

7. Wang XN, Wang L, Zheng DZ, Chen S, Shi W, Qiao XY, Jiang YP, Tang LJ, Xu YG, Li YJ. Oral immunization with a Lactobacillus casei-based antiporcine epidemic diarrhoea virus (PEDV) vaccine expressing microfold cell-targeting peptide Co1 fused with the COE antigen of PEDV. Journal of Applied Microbiology.J Appl Microbiol. 2018,124(2):368-378.

8. Wang X, Wang L, Huang X, Ma S, Yu M, Shi W, Qiao X, Tang L, Xu Y, Li Y. Oral Delivery of Probiotics Expressing Dendritic Cell-Targeting Peptide Fused with Porcine Epidemic Diarrhea Virus COE Antigen:A Promising Vaccine Strategy against PEDV.Viruses. 2017,9(11):E312.

9. MeilingYu, Li Wang, Sunting Ma , Xiaona Wang ,Yusai Wang ,Ya Xiao,Yanping Jiang, Xinyuan Qiao, Lijie Tang, Yigang Xu*, Yijing Li*. Immunogenicity of eGFP-marked recombinant Lactobacillus casei against transmissible gastroenteritis virus and porcine epidemic diarrhea virus. Viruses. 2017,9:274.


近五年授权的专利等情况

1、蓝舌病病毒型特异性竞争ELISA检测试剂盒及其应用,中国,ZL201710415171.42019,第2

2、用于蓝舌病病毒型特异性检测的竞争ELISA检测试剂盒及其应用,中国,ZL201710318544.62019,第2

3、一种鸡骨髓源树突细胞靶向肽SP及其用途,中国,ZL201711448093.42019,第2

4、一种鸡骨髓源树突细胞靶向肽AH及其用途,中国,ZL201711446581.12019,第3


其他获奖及荣誉称号