姓名:石宝明
性别:男
出生年月:1974-05-06
职称:二级教授
办公电话:13091863728
工作单位:东北农业大学动物科学技术学院
E-mail:shibaoming1974@163.com
开设研究生课程情况
课程编号 课程名称 课程级别 学时
105343 动物营养与饲料科学学科博士研讨班 博士研究生 16
近五年主持科研项目概况

1. 2023-2028,生物饲料功效评定与技术创新,横向课题,主持。

2. 2024-2027, 异丁酸钠介导肠道菌群-G蛋白偶联受体-iTreg调控仔猪肠道健康的分子机制,国家自然科学基金,主持。

3. 2023-2026,寒区生物发酵饲料新产品创制及应用,省高校协同创新成果项目,主持。

4. 2021-2026,寒冷环境下家庭牧场生长肥育猪动态营养需求与营养精准供给技术,国家重点研发项目子课题,主持。

5. 2021-2024,畜禽营养减排与发酵饲料技术研发. 黑龙江省“百千万”工程科技重大专项课题,主持。

6. 2021-2024,草甘膦介导TET3蛋白对母猪胚胎DNA甲基化的影响及分子机制研究,国家自然科学基金,主持。

7.  2019-2022,猪核受体PXR/CAR信号通路在农药草甘膦脱毒中的作用及其调控机制研究, 黑龙江省自然科学基金杰出青年项目,主持。

8. 2019-2022,氧化油脂致母猪乳腺损伤及子代氧化应激的分子机制和生物抗氧化剂保护作用的研究,国家自然科学基金,主持。

9. 2018 -2020,地方猪精准营养与特色饲料资源开发与应用示范,国家重点研发计划主持。

10. 2018-2020,优质高效绿色饲料配制及无抗饲养技术集成与示范国家重点研发计划子课题,主持。

11. 2018-2020, 民猪及杂交猪精准营养与无抗饲料开发,黑龙江省省属高校科技成果研发项目,主持。

12. 2017-2020,母猪乳中脂肪球粒径大小变异的生理与营养调控机制研究 国家自然科学基金,主持。


近五年项目获奖概况

1. 国家科技进步二等奖

2.神农中华农业科技奖优秀创新团队奖

3.黑龙江省科技进步奖二等奖

4. 东北农业大学优秀教学成果一等奖

5. 第三届全国大学生动物科学专业技能大赛 团体一等奖指导教师)

6. 第三届全国大学生动物科学专业技能大赛 荣获饲料原料快速鉴定与掺假识别——掺假鱼粉的鉴定项目 二等奖 (指导教师)


近五年代表性著作、论文

1.   Xinyu Liu, Xinke Wei, Ye Feng, Huawei Liu, Jiaqi Tang, Feng Gao and Baoming Shi *, Supplementation with Complex Dietary Fiber during Late Pregnancy and Lactation Can Improve Progeny Growth Performance by Regulating Maternal Antioxidant Status and Milk Quality , Antioxidants 2024, 13: 22. 

2.   Feng Gao, Wentao Zhang, Mingming Cao, Xinyu Liu, Tingting Han, Wei He, Baoming Shi* and Zhigang Gu*, Maternal supplementation with konjac glucomannan improves maternal microbiota for healthier offspring during lactation, J Sci Food Agric 2024; 104: 3736–3748

3.   Feng Gao, Haiyang Liu, Yongqing Du, Xiuyu Fang, Baojing Cheng, and Baoming Shi*Dietary Resveratrol Ameliorates Hepatic Fatty Acid Metabolism and Jejunal Barrier in Offspring Induced by Maternal Oxidized Soybean Oil ChallengeJournal of Agricultural and food chemistry, 2024, 72, 37303740.

4.   Wei He, Hongwei Ding, Ye Feng, Xinyu Liu, Xiuyu Fang, Feng Gao and Baoming Shi*Dietary-fat supplementation alleviates cold temperature-induced metabolic dysbiosis and barrier impairment by remodeling gut microbiotaFood & Function 2024,15,1443–1459

5.   Feng Gao, Xin Guan, Wentao Zhang, Tingting Han, Xinyu Liu, and Baoming Shi* Oxidized Soybean Oil Evoked Hepatic Fatty Acid Metabolism Disturbance in Rats and their OffspringJournal of Agricultural and Food Chemistry20237113483-13494

6.   Jianwei Qin, Xinke Wei, Mingming Cao and Baoming Shi*Non-12α-Hydroxylated Bile Acids Improve Piglet Growth Performance by Improving Intestinal Flora, Promoting Intestinal Development and Bile Acid SynthesisAnimals 2023, 133380. 

7.   Wei He, Zheng Yang , Hongwei Ding , Baoming Shi*Dietary supplementation with fermented wheat bran improves the inflammatory state and intestinal health in pigsLivestock Science2023274105286. 

8.   Teng Teng; Guodong Sun; Hongwei Ding; Xin Song; Guangdong Bai; Baoming Shi*; Tingting Shang*Characteristics of glucose and lipid metabolism and the interaction between gut microbiota and colonic mucosal immunity in pigs during cold exposure, Journal of Animal Science and Biotechnology, 20231484. 

9.  Feng Gao, Chuanqi Wang , Wentao Zhang, Baoming Shi*Effects of oxidized soybean oil on the performance of sows and jejunum health of suckling pigletsJournal of Animal Physiology and Animal Nutrition2023,107:830–838. 

10.  Yanan Gao; Qingwei Meng; Jianwei Qin; Qianqian Zhao; Baoming Sh*Resveratrol alleviates oxidative stress induced by oxidized soybean oils and improves gut function via changing gut microbiota in weaned pigletsJournal of Animal Science and Biotechnology20231454

11.  Teng Teng, Xin Song, Guodong Sun, Hongwei Ding, Haoyang Sun, Guangdong Bai, Baoming Shi*Glucose supplementation improves intestinal amino acid transport and muscle amino acid pool in pigs during chronic cold exposureAnimal Nutrition202312360-374 

12.  Guangdong Bai, Yingbin Zou, Wentao Zhang, Xu Jiang, Jianwei Qin, Teng Teng, Haoyang Sun, Baoming Shi⁎Perinatal exposure to high concentration glyphosate-based herbicides induces intestinal apoptosis by activating endoplasmic reticulum stress in offspringScience of the Total Environment2023 8659):161223

13.  Guodong Sun; Wei Su; Jiaxin Bao; Teng Teng; Xin Song; Jiawei Wang; Baoming Shi*Dietary full-fat rice bran prevents the risk of heart ferroptosis and imbalance of energy metabolism induced by prolonged cold stimulationFood & Function2023143):1530-1544. 

14.  Teng T, Sun G, Song X, Shi B*. The Early Faecal Microbiota Transfer Alters Bile Acid Circulation and Amino Acid Transport of the Small Intestine in Piglets. Journal of Animal Physiology and Animal Nutrition20231072):564-573. 

15.  GuangdongBai Xu Jiang Jianwei QinYingbin Zou Wentao ZhangTengTeng BaomingShi*HaoyangSun*Perinatal exposure to glyphosate-based herbicides impairs progeny health and placental angiogenesis by disturbing mitochondrial function. Environment International. 2022,170107579

16.  Guodong Sun, Xin Song, Yingbin Zou, Teng Teng, Lin Jiang, Baoming Shi * . Dietary Glucose Ameliorates Impaired Intestinal Development and Immune Homeostasis Disorders Induced by Chronic Cold Stress in Pig Model. International Journal of Molecular Sciences, 2022,23:7730. 

17.  Xuan Zhao, Lin Jiang, Xiuyu Fang, Zhiqiang Guo, Xiaoxu Wang, Baoming Shi* and Qingwei Meng*. Host-microbiota interaction-mediated resistance to inflammatory bowel disease in pigs. Microbiome, 202210115 

18.  Teng Teng , Hao Yang, Tianqi Xu, Guodong Sun , Xin Song, Guangdong Bai and Baoming Shi* Activation of Inflammatory Networks in the Lungs Caused by Chronic Cold Stress Is Moderately Attenuated by Glucose Supplementation. International Journal of Molecular Sciences, 2022, 23, 10697.

19.  Chuanqi Wang,† Haoyang Sun,† Xu Jiang, Xin Guan, Feng Gao, and Baoming Shi* Maternal Oxidized Soybean Oil Administration in Rats during Pregnancy and Lactation Alters the Intestinal DNA Methylation in Offspring, Journal of Agricultural and food chemistry, 2022,70:6224-6238. 

20.  Guangdong Bai#Ruiying Zhou#Xu JiangYingbin ZouBaoming Shi*Glyphosate-based herbicides induces autophagy in IPEC-J2 cells and the intervention of N-acetylcysteine. Environmental Toxicology. 2022, 378:1878–1890

21.  Shengnan Qiu & Yang Liu & Yanan Gao & Huiyang Fu & Baoming Shi*Response of the nuclear xenobiotic receptors to alleviate glyphosate-based herbicide-induced nephrotoxicity in weaned piglets, Environmental Science and Pollution Research, 2022, 292707-2717

22.  Feng Gao, Zhiqiang Guo, Yanan Gao, Chuanqi Wang, Huiting Wang, Xinxin Yao and Baoming Shi*Maternal oxidized soybean oil exposure in rats during lactation damages offspring kidneys via Nrf2/HO-1 and NF-κB signaling pathway, Journal of The Science of Food and Agriculture, 2022, 102: 3119–3129. 


近五年授权的专利等情况

1. 一种具有抑制多种致病菌微生物生长的民猪源枯草芽孢杆菌 

2.一种不含有豆粕和磷酸氢钙的育肥猪饲料

3一种饲料霉菌毒素吸附剂及其制备方法

4.一种提高母猪初乳中免疫球蛋白含量的饲料添加剂

5.一种减少母猪乳中脂肪球颗粒粒径的饲料添加剂

6.提高抗病性和抑制致病菌生长的民猪源暹罗芽孢杆菌

7.一种民猪肠道中可抑制多种有害菌生长的贝莱斯芽孢杆菌

其他获奖及荣誉称号

1.  黑龙江省政府特殊津贴

2.  黑龙江省“头雁团队”- 畜禽健康养殖创新团队

3.  东北农业大学首席教授

4. 东北农业大学“突出贡献奖

5. 黑龙江省杰出青年科学基金获得者

6.颐和青年创新奖

7.中国畜牧兽医学会动物营养学分会常务理事

8.黑龙江省动物营养与饲料学分会理事长