姓名:王加强
性别:男
出生年月:1987-08-06
职称:教授
办公电话:15110002886
工作单位:东北农业大学生命科学学院
E-mail:wangjiaqiang@neau.edu.cn
开设研究生课程情况
课程编号 课程名称 课程级别 学时
109223 细胞与分子生物学前沿研究方法 核心课 32
近五年主持科研项目概况

(1) 2020-01 ~ 2023-12,国家自然科学基金委员会,面上项目,31970588,大鼠-小鼠异种杂合二倍体胚胎干细胞中异源基因组的互作模式的研究,58万元。

(2) 2020-07 ~ 2023-07,黑龙江省自然科学基金委员会,优秀青年项目,YQ2020C003,LincGET通过Paraspeckle的相变调控早期胚胎发育,10万元。

近五年项目获奖概况

近五年代表性著作、论文

(1) Jiaqiang Wang*, Yiwei Zhang, Jiaze Gao, Guihai Feng, Chao Liu, Xueke Li, Pengcheng Li, Zhonghua Liu, Falong Lu, Leyun Wang*, Wei Li*, Qi Zhou*, and Yusheng Liu*, Alternative splicing of CARM1 regulated by LincGET-guided paraspeckles biases the first cell fate in mammalian early embryos. Nature Structural & Molecular Biology, 2024. DOI: 10.1038/s41594-024-01292-9. (IF: 18.361, 1区TOP) (第一作者+共同通讯作者)

(2) Yusheng Liu, Falong Lu*, Jiaqiang Wang*, Sequencing of Transcriptome-Wide Poly(A) Tails by PAIso-seq. Methods in molecular biology, 2024, 2723: 215-232. (最后通讯作者)

(3) Tianyao He, Jinyu Peng, Shu Yang, Dongsong Liu, Shuang Gao, Yanlong Zhu, Zhuang Chai, Byeong Chun Lee, Renyue Wei, Jiaqiang Wang*, Zhonghua Liu*, Jun-Xue Jin*, SINE-Associated LncRNA SAWPA Regulates Porcine Zygotic Genome Activation. Advanced Science, 2023. (IF: 15.10, 1区TOP) (共同通讯作者)

(4) Sunyang Ying#, Pengcheng Li#, Jiaqiang Wang#, Kaiqiong Chen#, Yu Zou, Moyu Dai, Kai Xu, Guihai Feng, Changjian Zhang, Haiping Jiang, Wei Li*, Ying Zhang*, Qi Zhou*. tRF-Gln-CTG-026 ameliorates liver injury by alleviating global protein synthesis. Signal Transduct Target Ther, 2023, 8(1): 144. (IF: 38.104, 1区TOP) (共同第一作者)

(5) Yusheng Liu#, Han Zhao#, Fanghong Shao#, Yiwei Zhang#, Hu Nie, Jingye Zhang, Cheng Li, Zhenzhen Hou, Zi-Jiang Chen, Jiaqiang Wang*, Bing Zhou*, Keliang Wu*, Falong Lu*. Remodeling of maternal mRNA through poly(A) tail orchestrates human oocyte-to-embryo transition. Nature Structural & Molecular Biology, 2023, 30(2): 200-215.  (IF: 18.361, 1区TOP) (共同通讯作者)

(6) Yusheng Liu#*, Hu Nie#, Yiwei Zhang#, Falong Lu*, Jiaqiang Wang*, Comprehensive analysis of mRNA poly(A) tails by PAIso-seq2, Science China-Life Sciences, 2023, 66(1): 187-190. (IF: 10.372, 1区TOP) (最后通讯作者)

(7) Shuang Wu, Yiwei Zhang, Lan Yao, Jiaqiang Wang*, Falong Lu*, and Yusheng Liu*. m6A-modified RNA possess distinct poly(A) tails. J Genet Genomics. 2022, 50(3): 208-211. (IF: 5.723, 2区) (共同通讯作者)

(8) Yusheng Liu*, Yiwei Zhang, Jiaqiang Wang*, Falong Lu*. Transcriptome-wide measurement of poly(A) tail length and composition at subnanogram total RNA sensitivity by PAIso-seq. Nature Protocols, 2022, 17(9), 1980-2007. (IF: 17.021, 1区TOP) (共同通讯作者) 

(9) Xin Li#, Jiaqiang Wang#, Leyun Wang#, Yuanxu Gao#, Guihai Feng, Gen Li, Jun Zou, Meixin Yu, Yu Fei Li, Chao Liu, Xue Wei Yuan, Ling Zhao, Hong Ouyang, Jian-Kang Zhu*, Wei Li*, Qi Zhou*, Kang Zhang*. Lipid metabolism dysfunction induced by age-dependent DNA methylation accelerates aging. Signal Transduct Target Ther, 2022, 7(1), 162. (IF: 38.104, 1区TOP) (共同第一作者)

近五年授权的专利等情况

(1) 王加强, 王乐韵; 一种判定蛋白质能否发生液-液相分离的方法, 2021-10-19, 中国, ZL201910958709.5.

其他获奖及荣誉称号

(1) 2022-05,东北农业大学“青年五四奖章”。

(2) 2022-09,东北农业大学“优秀教师”。