姓名:张瑞莉
性别:女
出生年月:1970-01-31
职称:教授
办公电话:13684626871
工作单位:东北农业大学
E-mail:zhangruili@neau.edu.cn
开设研究生课程情况
课程编号 课程名称 课程级别 学时
106333 超微病理学 博士研究生课程 48
106246 基础兽医学科前沿专题讲座与研讨 博士研究生课程 48
近五年主持科研项目概况

1. 提高猪生长性能和免疫功能的中药饲料添加剂研发与应用. 哈尔滨市科学技术局项目,主持,2020.10-2022.10

2.  MDA5TLR3信号转导通路在IBDV致雏鸡法氏囊免疫损伤中的作用机制. 国家自然科学基金资助项目,主持,2013.01-2016.12.

近五年项目获奖概况

主编的《动物病理解剖学实验指导》获东北农业大学优秀教材奖。

近五年代表性著作、论文

1. Linghuan Luo, Ming Ge, Yiming Sun, Yihan Hu, Xiaoyi Yang, Ruili Zhang. New findings on the antagonism of the environmental chemical toxicity 2-ethylhexyl diphenyl phosphate: Glycyrrhizic acid as an Nrf2 activator targets Nrf2/ROS/STAT3 signalling crosstalk to alleviate thymic injury in chicks[J]. Poultry Science, 2025,104:104918.

2. Yiming Sun, Ruili Zhang, Jiali Li, Yihan Hu, Haolin Zhang, Xiangjie Wang, Yi Yang, Haibin Wang Ming Ge. 2-Ethylhexyl diphenyl phosphate induces lung oxidative stress and pyroptosis in chicks[J]. Science of the Total Environment. 2025,962:178453.

3. Yihan Hu , Yiming Sun , Haolin Zhang , Linghuan Luo, Haibin Wang, Ruili Zhang, Ming Ge, 2-ethylhexyl diphenyl phosphate exposure induces duodenal inflammatory injury through oxidative stress in chickens[J]. Ecotoxicology and Environmental Safety2024,283:116784.

4. 陈敬宜,于淼,张金洋,樊堃,杨桂君,葛铭,张瑞莉. 铁死亡参与镉暴露鸡肝损伤的研究[J], 畜牧兽医学报, 2023, 54(02): 787-802.

5. Yi Yang, Xiangjie Wang, Haolin Zhang, Jiali Li, Jingyi Chen, Miao Yu, Guangxing Li, Ruili Zhang, Ming Ge. Oxidative Stress and Ferroptosis Involved in 2-ethylhexyl diphenyl phosphate-induced Hepatotoxicity in Chicken[J], Chemico-Biological Interactions, 2022, 368:110216.

6. Miao Yu, Ruyue Li, Meishuo Wan, Jingyi Chen, Xudong Shen, Guangxing Li, Ming Ge, Ruili Zhang. MDA5 Attenuate Autophagy in Chicken Embryo Fibroblasts Infected with IBDV[J], Br Poult Sci, 2022, 63(2): 154-163.

7. Xudong Shen, Zequn Tang, Yu Bai, Meishuo Wan, Miao Yu, Jingyi Chen, Guangxing Li, Ruili Zhang, Ming Ge. Astragalus Polysaccharide Protects Against Cadmium-Induced Autophagy Injury through Reactive Oxygen Species (ROS) Pathway in Chicken Embryo Fibroblast[J], Biol Trace Elem Res, 2022, 200 (1): 318-329.

8. Danlei Xu, Xiangqi Teng, Rong Guo, Xudong Shen, Meishuo Wan, Guangxing Li, Ruili Zhang, Ming Ge. Metabonomic Analysis of Hypophosphatemic Laying Fatigue Syndrome in Laying Hens[J], Theriogenology, 2020, 156: 222-235.

近五年授权的专利等情况

1. 提高猪繁殖、免疫性能及抗病能力的饲料添加剂及制备方法,国家发明专利,ZL202310212607.5,2024-3-19,第一发明人

2. 抗chMDA5蛋白单克隆抗体及其制备方法和 应用, 国家发明专利,ZL201410697397.4,2017-2-22, 第一发明人

其他获奖及荣誉称号

中国兽医病理学家成员

东北农业大学优秀教师