姓名:赵李霞
性别:女
出生年月:1981-12-15
职称:教授
办公电话:19845076986
工作单位:东北农业大学
E-mail:zhaolixia@neau.edu.cn
开设研究生课程情况
课程编号 课程名称 课程级别 学时
211307 农药化学 研究生课程 32
111210 博士专业英语实践 研究生课程 16
近五年主持科研项目概况

1. 黑龙江省自然科学基金联合基金重点项目,新型白化类PPO抑制剂除草剂的开发与分子作用机制研究ZL2024C009),2025.1至2027.12,50万元,主持。

2. 黑龙江省优秀青年教师基础研究支持计划基于天然产物分子碎片设计新型除草剂及其分子作用机制研究(YQJH2023204)2024.1至2026.12,10万,主持。

3. 南通江山农药化工股份有限公司新型PPO类除草剂研发2023HX20011,2023.102026.10,280万元,主持。

3. 黑龙江省博士后科研启动金, , 基于药效团拼接设计的新型PPO抑制剂的合成、除草活性及QSAR研究(LBH-Q19083,2020.012022.12,6万元,主持。

近五年项目获奖概况
近五年代表性著作、论文

1. Ya-Tong Liu1, Qian-Qian Zhang1, Si-Yi Yao, Ke-Yu Zhao, Han-Wen Cui, Hua-Yong Zhao, Jing-Yi Li, Yue-Li Zou*, Li-Xia Zhao*. A near-infrared multifunctional fluorescent bio-probe with large stokes shift and high quantum yield for effective determination of heavy metal lead and pesticide glyphosate in vitro and vivo. Journal of Hazardous Materials, 2025, 486: 137017.(中科院一区,IF=12.2

2. Li-Xia Zhao, Kai Luo, Xian-Da Guo, Yue-Li Zou, Shuang Gao, Ying Fu*, Fei Ye*. Design, synthesis, and biological activity evaluation of novel phenoxypyridine derivatives containing acylthiourea fragments as protoporphyrinogen oxidase inhibitor herbicides. Journal of Agricultural and Food Chemistry, 2025, 73(9): 5020–5032.(中科院一区,IF=5.7

3. Ya-Tong Liu1, Yue Hou1, Si-Yi Yao, Ke-Yu Zhao, Han-Wen Cui, Meng-Xun Zhang, Hao Wang, Yue-Li Zou*, Li-Xia Zhao*. A novel dual-responsive NIR fluorescent probe based on isophorone: Real-time detection of Al3+ in vivo and colorimetric sensing of pH through smartphone. Journal of Environmental Chemical Engineering, 2025, 13: 115620.(中科院二区,IF=7.4

4. Ya-Tong Liu1, Qian-Qian Zhang1, Si-Yi Yao, Han-Wen Cui, Yue-Li Zou*, Li-Xia Zhao*. Dual-recognition “turn-off-on” fluorescent Biosensor triphenylamine-based continuous detection of copper ion and glyphosate applicated in environment and living system, Journal of Hazardous Materials, 2024, 477, 135216.(中科院一区,IF=12.2

5. Li-Xia Zhao, Kun-yu Chen, Kai Luo, Xiao-li He, Shuang Gao, Ying Fu, Yue-Li Zou*, Fei Ye*. Design, synthesis and biological activity of novel phenyltriazolinone PPO inhibitors containing five-membered heterocycles. Journal of Agricultural and Food Chemistry, 2024, 72, 11, 5625-5635.(中科院一区,IF=5.7

6. Li-Xia Zhao, Wei Hu, Zi-Bin Jiang, Jia-Yu Wang, Kui Wang, Shuang Gao, Ying Fu*, Fei Ye*. Design, synthesis, and bioactivity of novel 2-(arylformyl)cyclohexane-1,3-dione derivatives as HPPD inhibitors. Journal of Agricultural and Food Chemistry, 2023, 71, 46, 17678-17688. (中科院一区,IF=5.7

7. Li-Xia Zhao, Kun-yu Chen, Xiao-li He, Yue-Li Zou, Shuang Gao, Ying Fu*, Fei Ye*. Design, synthesis, and biological activity determination of novel phenylpyrazole protoporphyrinogen oxidase inhibitor herbicides containing five-membered heterocycles. Journal of Agricultural and Food Chemistry, 2023, 71, 39, 14164-14178.(中科院一区,IF=5.7

8. Li-Xia Zhao, Kun-yu Chen, Hua-yong Zhao, Yue-Li Zou, Shuang Gao, Ying Fu*, Fei Ye*. Design, synthesis and biological activity determination of novel phenylpyrazole protoporphyrinogen oxidase inhibitor herbicides. Pesticide Biochemistry and Physiology, 2023, 196, 105588.(中科院一区,IF=4.6

9. Xin-Yu Leng, Li-Xia Zhao, Shuang Gao, Fei Ye*, Ying Fu*. Review on the discovery of novel natural herbicide safeners. Journal of Agricultural and Food Chemistry, 2023, 71, 30, 11320-11331.(中科院一区,IF=5.7

10. Bo-Wen Ye, Li-Xia Zhao, Zi-Wei Wang, Juan Shi, Xin-Yu Leng, Shuang Gao, Ying Fu*, Fei Ye*. Design, synthesis, and bioactivity of novel ester-substituted cyclohexenone derivatives as safeners. Journal of Agricultural and Food Chemistry, 2023, 71, 15, 5973-5990.(中科院一区,IF=5.7

11. Li-Xia Zhao, Kun-Yu Chen, Kai-Bo Xie, Jia-Jun Hu, Meng-Yu Deng, Yue-Li Zou, Shuang Gao, Ying Fu*, Fei Ye*. A benzothiazole-based “on-off” fluorescence probe for the specific detection of Cu2+ and its application in solution and living cells. Dyes and Pigments, 2023, 210, 110943.(高被引论文,中科院二区,IF=4.1

12. Li-Xia Zhao, Xiao-Li He, Kai-Bo Xie, Jia-Jun Hu, Meng-Yu Deng, Yue-Li Zou, Shuang Gao, Ying Fu*, Fei Ye*. A novel isophorone-based fluorescent probe for recognition of Al3+ and its bioimaging in cells and plants. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 285, 121882.(高被引论文,中科院二区,IF=4.3

13. Li-Xia Zhao, Jian-Feng Peng, Feng-Yi Liu, Yue-Li Zou, Shuang Gao, Ying Fu*, Fei Ye*. Design, synthesis, and herbicidal activity of diphenyl ether derivatives containing a five-membered heterocycle. Journal of Agricultural and Food Chemistry, 2022, 70, 4, 1003-1018.高被引论文,中科院一区,IF=5.7

13. Li-Xia Zhao, Jian-Feng Peng, Feng-Yi Liu, Yue-Li Zou, Shuang Gao, Ying Fu*, Fei Ye*. Discovery of novel phenoxypyridine as promising protoporphyrinogen IX oxidase inhibitors. Pesticide Biochemistry and Physiology. 2022, 184, 105102.(中科院一区,IF=4.6

14. Ling Jia1, Li-Xia Zhao1, Fang Sun, Jie Peng, Jia-Yu Wang, Xin-Yu Leng, Shuang Gao, Ying Fu*, Fei Ye*. Diazabicyclo derivatives as safeners protect cotton from injury caused by flumioxazin. Pesticide Biochemistry and Physiology. 2022, 187, 105185.(中科院一区,IF=4.6

15. Li-Xia Zhao, Zhi-Xin Wang, Jian-Feng Peng, Yue-Li Zou, Yong-Zhuo Hui, Chen Yong-Zheng, Shuang Gao, Ying Fu*, Fei Ye*. Design, synthesis, and herbicidal activity of novel phenoxypyridine derivatives containing natural product coumarin. Pest Management Science, 2021, 196, 10, 1-14.(中科院一区,IF=4.3

16. Li-Xia Zhao, Zhi-Xin Wang, Yue-Li Zou, Shuang Gao, Ying Fu*, Fei Ye*. Phenoxypyridine derivatives containing natural product coumarins with allelopathy as novel and promising proporphyrin IX oxidase-inhibiting herbicides: Design, synthesis and biological activity study. Pesticide Biochemistry and Physiology, 2021, 177, 104897.(中科院一区,IF=4.6

17. Hao-Min Song1, Li-Xia Zhao1, Shuai-Qi Zhang, Tong Ye, Ying Fu*, Fei Ye*. Design, synthesis, structure-activity relationship, molecular docking, and herbicidal evaluation of 2-cinnamoyl-3-hydroxycyclohex-2-en-1-one derivatives as novel 4-hydroxyphenylpyruvate dioxygenase inhibitors. Journal of Agricultural and Food Chemistry, 2021, 69(43): 12621-12633.(中科院一区,IF=5.7

18. Zi-Wei Wang1, Li-Xia Zhao1, Peng Ma, Tong Ye, Ying Fu*, Fei Ye*. Fragments recombination, design, synthesis, safener activity and CoMFA model of novel substituted dichloroacetylphenyl sulfonamide derivatives. Pest Management Science. 2021, 77(4): 1724-1738.(中科院一区,IF=4.3

19. Ke-Liang Guo1, Li-Xia Zhao1, Zi-Wei Wang, Ying-Chao Gao, Juan-Juan Li, Shuang Gao, Ying Fu*, Fei Ye*. Design, synthesis, and bioevaluation of substituted phenyl isoxazole analogues as herbicide safeners. Journal of Agricultural and Food Chemistry, 2020, 68: 10550-10559.(中科院一区,IF=5.7

20. Li-Xia Zhao, Mao-Jun Jiang, Jia-Jun Hu, Yue-Li Zou, Yuan Cheng, Tao Ren, Shuang Gao, Ying Fu*, Fei Ye*. Design, synthesis, and herbicidal activity of novel diphenyl ether derivatives containing fast degrading tetrahydrophthalimide. Journal of Agricultural and Food Chemistry, 2020, 68, 3729-3741.高被引论文,中科院一区,IF=5.7

21. Li-Xia Zhao, Jia-Jun Hu, Zhi-Xin Wang, Min-Lei Yin, Yue-Li Zou, Shuang Gao, Ying Fu*, Fei Ye*. Novel phenoxy-(trifluoromethyl)pyridine-2-pyrrolidinone-based inhibitors of protoporphyrinogen oxidase: design, synthesis, and herbicidal activity. Pesticide Biochemistry and Physiology, 2020, 104684..(中科院一区,IF=4.6

近五年授权的专利等情况

1. 邹月利刘娅彤赵李霞张茜茜曹佳琪比色分子探针及其制备方法和应用专利号:ZL2024104257579申请时间:2024.4.9授权时间:2025.02.18

2. 叶非,付颖,赵李霞,贾玲,彭婕。一种嘌呤类衍生化合物、制备方法及其应用专利号:ZL 202311400343.2申请时间:2023.10.26授权时间:2024.05.24

3. 赵李霞;付颖;宋若男;叶非;邹月利;贺肖利.一种含有杂环结构的三唑啉酮类化合物、制备方法及其应用专利号:ZL 202311601896.4申请时间:2023.11.28授权时间:2024.05.10

4. 赵李霞,叶非,付颖。一种用于单子叶作物的除草组合物及其用途。中国发明专利。专利号:ZL201511033695.4。申请时间:2015.12.28。授权时间:2018.6.19

5. 叶非赵李霞付颖高爽王紫薇。一种环己烯酮类安全剂及其应用、除草组合物及其应用。专利号:ZL202211440219.4申请时间:2022.11.17授权时间:2023.07.14

6. 付颖,叶非,赵李霞,陈文更除草组合物及其应用中国发明专利专利号:ZL201711383039.6申请时间:2017.12.20授权时间:2020.03.17

7. 叶非,付颖,赵李霞,高爽,吴世龙用于玉米生长的区域防治有害杂草的除草组合物及其用途中国发明专利专利号:ZL201810750196.4申请时间:2018.07.10授权时间:2020.03.17

8. 付颖,叶非,赵李霞,康晶欣,王姣一种用于禾本科作物田的除草剂及其用途中国发明专利专利号:ZL201610078256.3申请时间:2016.01.29授权时间:2018.01.30

9. 付颖,叶非,赵李霞,曲丽华。N-二氯乙酰基-6,7-二氯-1,2,3,4-四氢喹喔啉及其制备方法。专利号:ZL201310196037.1。申请时间:2013.05.24。授权时间:2015.05.20

其他获奖及荣誉称号

1. 东北农业大学师德师风先进个人2022.9

2. 东北农业大学校级青年教学名师2021.5

3. 东北农业大学青年五四奖章,2020.5